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For your patients with pulmonary arterial hypertension (PAH, WHO Group I)

TREAT EARLY WITH UPTRAVI®1

PROVEN
EFFICACY

Studied in GRIPHON, the largest PAH pivotal trial with the longest endpoint evaluation period of any prostacyclin pathway therapy1-3

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ESTABLISHED
SAFETY

Consistent safety profile across GRIPHON (N=1156) and open-label extension (OLE)1,4

See Safety

ORAL
ADMINISTRATION

  • Twice-daily dosing1
  • No needles, pumps, or inhalers1*
Explore Dosing

*UPTRAVI® IV is available for patients who are temporarily unable to take oral therapy.

FC=Functional Class; GRIPHON=Prostacyclin (PGI2) Receptor Agonist In Pulmonary Arterial HypertensiON; IV=intravenous; WHO=World Health Organization.

References: 1. UPTRAVI® (selexipag) full Prescribing Information. Actelion Pharmaceuticals US, Inc. 2. Sitbon O, Gomberg‍-‍Maitland M, Granton J, et al. Clinical trial design and new therapies for pulmonary arterial hypertension. Eur Respir J. 2019‍;‍53‍(‍1‍)‍:‍1801908. doi‍:‍10‍.‍1183‍/‍13993003‍.‍01908‍-‍2018. 3. Data on file. Actelion Pharmaceuticals US, Inc. Length and Population Size of PAH Pivotal Trials Confirmation. June 2024. 4. Galiè N, Gaine S, Channick R, et al. Long‍-‍term survival, safety and tolerability with selexipag in patients with pulmonary arterial hypertension: results from GRIPHON and its open‍-‍label extension. Adv Ther. 2022‍;‍39(‍1‍)‍:‍796‍-‍810.